Palomo is a Spanish and Italian surname. Notable people with the surname include:
Ana Belén Palomo (born 1977), freestyle swimmer from Spain Eduardo Palomo (1962–2003), Mexican actor Tony Palomo (1931–2013), Guamanian historian and politician Lorenzo Palomo (1938–2024), Spanish conductor and composer Víctor Palomo (1948–1985), Spanish Grand Prix motorcycle racing driver Florencio Palomo Valencia, Governor of Yucatán (1936–1938) Elena Huelva Palomo (2002–2023), Spanish cancer activist and writer Víctor Mena Palomo, Governor of Yucatán (1953–1958)