Bille is a Danish surname. Bille is also a Hindu Vaishya surname in India. Notable people with the surname include:
Anders Bille (1600–1657), Danish general Beate Bille (disambiguation), multiple people Edmond Bille (1878–1959), Swiss artist Ejler Bille (1910–2004), Danish artist Gaëtan Bille (born 1988), Belgian cyclist Irene Ibsen Bille (1901–1985), Norwegian writer and playwright Jens Bille (1531–1575), Danish courtier and compiler of a poetry manuscript, Jens Billes visebog Joen Bille (born 1944), Danish actor Josef Bille (1944–2023), German physician Kristina Bille (born 1986), Danish handball player Michael Bille (1769–1845), Danish admiral S. Corinna Bille (1912–1979), Swiss writer Steen Andersen Bille (1751–1833), Danish admiral Steen Andersen Bille (1797–1883), Danish admiral Steen Bille, Danish diplomat Svend Bille (1888–1973), Danish actor Téclaire Bille (1988–2010), Equatoguinean footballer