James Calthorpe may refer to:
James Calthorpe of Cockthorpe (c. 1558–1614), Sheriff of Norfolk in 1614 James Calthorpe of East Barsham (1604–1652), Sheriff of Norfolk in 1643 Sir James Calthorpe (Roundhead) (died 1658), Sheriff of Suffolk, knighted by the Lord Protector Olive Cromwell James Calthorpe (Yeoman of the Removing Wardrobe) (1699–1784), English politician and courtier
See also Calthorpe (surname)