Skrine is a surname. It may refer to:
Arthur Wallace Skrine (1885–?), British colonial administrator in Anglo-Egyptian Sudan Buster Skrine (born April 26, 1989), U.S. football player Sir Clarmont Percival Skrine (1888–1974), British civil servant and administrator of the British Raj; son of Francis. Francis Henry Skrine (1847–1933), British civil servant and administrator of the British Raj; father of Sir Clarmont.