Seppänen is a Finnish surname derived from the occupation of blacksmith ("seppä"). Notable people with the surname include:
Elias Seppänen (born 2003), Finnish racing driver Ensio Seppänen (1924–2008), Finnish sculptor and professor Esko Seppänen (1946–2025), Finnish politician Iiro Seppänen (born 1975), Finnish producer, director and author Sara Seppänen (born 1982), Finnish politician Timo Seppänen (born 1987), Finnish ice hockey player Tytti Seppänen (born 1980), Finnish politician