William Rice (by 1522 – 1588), of Medmenham, Buckinghamshire, was an English politician.

Family William Rice was the son of Mr. Rice and his wife Eden née Saunders, daughter of Thomas Saunders. He married Barbara Fuller.

Career He was a member (MP) of the parliament of England for Aylesbury in November 1554 and 1555, and for Lancaster in 1558.

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