Southerland may refer to:

Persons Clarence A. Southerland (1889–1973), Justice of the Delaware Supreme Court James Southerland, American professional basketball player Pug Southerland (1911-1949), American Navy fighter pilot during World War II Steve Southerland (Tennessee politician) (born 1955), member of the Tennessee House of Representatives Steve Southerland (Florida politician) (born 1965), United States Representative for Florida's 2nd District Thom Southerland (fl. 2000s–2010s), English theatre director William Henry Hudson Southerland (1852–1933), rear admiral in the United States Navy

Others USS Southerland (DD-743), a Gearing-class American destroyer Fort Southerland, Arkansas site of a Civil War engagement, part of the Camden Expedition