Apomastus schlingeri (misnomer Aptostichus schlingeri) is a species of venomous spiders belonging to a family of trapdoor spiders. They produce a complex of neurotoxins called aptotoxins. Both known species of the genus are found in the United States.
Venom
Apomastus schlingeri have a venom that is highly neurotoxic in effect. The neurotoxin is actually a complex of proteins called aptotoxins (Aps for short), which in turn belong to a group of neurotoxins called cyrtautoxins. There are at least nine different peptides, and most of them are directly paralytic and lethal to insect larvae. All of the peptides are voltage-gated sodium channel blockers. To date, Aps III is known to be the most potent peptide of all.
References
External links Taxonomy at UniProt NCBI Taxonomy Browser Taxonomy at ITIS Report Animal Diversity Web Venom information at ArchnoSpider Taxonomy at The Taxonomicon Comparative Taxinogenomics Database Global Species Taxon profile at BioLib