Sasscer is a surname, and may refer to:
Frederick Sasscer, Jr., attorney, journalist and educator from Upper Marlboro, Maryland Lansdale Ghiselin Sasscer, represented the fifth district of the state of Maryland in the United States House of Representatives for seven terms 1939–1953 Lansdale Ghiselin Sasscer, Jr., member of the Maryland House of Delegates, first elected in 1954
See also Digges-Sasscer house, an historic building in Upper Marlboro, Maryland Sasscer Tobacco Barn, an historic building in Brandywine, Maryland