Mangum is a surname. Notable people with the surname include:
Crystal Mangum, American woman who perpetrated the 2006 Duke University lacrosse rape hoax and later murdered her partner Dusty Mangum (born 1983), American football player Jake Mangum (born 1996), American baseball player Jeff Mangum (born 1970), American musician and songwriter John Mangum (disambiguation), several people Jonathan Mangum (born 1971), American actor and comedian Kris Mangum (born 1973), American football player Pete Mangum (1931–2000), American football player Tanner Mangum (born 1993), American football player Willie Person Mangum (1792–1861), American politician