Upper Main Street Historic District is a national historic district located at Lafayette, Indiana. Sixth Street was the City of Lafayette's eastern boundary when it was originally platted. By 1840, the boundary was extended to include Lake Erie and Wabash Railroad at Eleventh Street. This area became the cities commercial center. Businesses around Eleventh Street developed to meet the traveling publics needs. The Enterprise Hotel, at 1015 Main Street, as well as the Alt Heidelberg, American Lafayette and the Derby Hotel were early established by 1899.Interim Report Tippecanoe County Interim Report, Indiana Historic Sites and Structures Inventory; Historic Landmarks Foundation of Indiana; May 1990; pg. 95-98 Note: This includes , Site map, and Accompanying photographs

Significant structures 1873, Vollmer-Conrad Building, 1001 Main Street 1875, Enterprise Hotel, 1015 Main Street 1877, Beck Building, 731 Main Street 1877/1897, Carnahan Hall, 800 Main Street 1880/1919, Duplex, 612-614 Columbia Street 1884, Haderle Building, 1010 Main Street 1887, Krabbe Building, 1000-10`02 Main Street 1892-1893, Carnahan Building, 622 Main Street 1899, Weigle Townhouse, 932-925 Main Street 1915, D.L. Ross Building, 652-688 Main Street 1920-1921, Mars Theater, 111 North Sixth Street 1938, Lafayette Theater, 600 Main Street All structures are historically ‘Notable’ or ‘Outstanding’ examples within the Historic District. An ‘O’ rating signifies that the structure had enough historic or architectural significance to be considered for individual listing in the National Register of Historic Places. The ‘N’ rating signifies that the structure is above average and may, with further investigation be eligible for an individual listing. The contributing structures meet the basic inventory qualifications, but fails to meet individual merit, but in combination with other closely placed similar structures warrants inclusion in an historic district.

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See also Centennial Neighborhood District Downtown Lafayette Historic District Ellsworth Historic District Highland Park Neighborhood Historic District Jefferson Historic District Ninth Street Hill Neighborhood Historic District Perrin Historic District St. Mary Historic District

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