Newhouse is an English surname. Notable people with the surname include:
Alana Newhouse (born 1976), American writer and editor Dan Newhouse (born 1955), American politician Dave Newhouse (born 1953), American musician Donald Newhouse (1929–2026), American publisher Flower A. Newhouse (1909–1994), Christian mystic and spiritual teacher Fred Newhouse (1948–2025), American runner Joseph Newhouse (born 1942), American economist Julian O. Newhouse (1915–2006), American businessman and politician Mark Newhouse (born 1985), American poker player Neil Newhouse, American pollster Richard H. Newhouse, Jr. (1924–2002), American politician Robert Newhouse, (1950–2014), American football player Samuel Newhouse (1853–1930), American mining magnate from Utah Samuel Irving Newhouse, Sr. (1895–1979) American broadcasting businessman, magazine and newspaper publisher Samuel Irving Newhouse, Jr. (1927–2017), chairman and CEO of Advance Publications