Lesieur is a last name, and may refer to:
Art Lesieur (1907–1967), American ice hockey player Émile Lesieur (1885–1985), French rugby player Eugène Lesieur (1890–1975), French wrestler Jean-Pierre Lesieur (born 1935), French poet Georges Lesieur (1848–1931), French businessman Marie Lesieur (1799–1890), known as Marie Lesueur, French ballet dancer Stephen Lesieur, Swiss-born English diplomat