Hastrup is a Danish surname. Notable people with the surname include:

Jannik Hastrup (born 1941), Danish writer, film director, producer, illustrator and animator Kirsten Hastrup (born 1948), Danish anthropologist and professor Rune Hastrup (born 1991), Danish footballer Vibeke Hastrup (born 1958), Danish actress

See also Mads Vibe-Hastrup (born 1978), Danish golfer 16589 Hastrup, main-belt asteroid