Toledo is a surname of Spanish origin, after the city of Toledo. Notable people with the surname include:

Historical Saint Casilda of Toledo (died 1050), Spanish Catholic Saint Eleonora di Garzia di Toledo (1553–1576), wife of Pietro de' Medici Eleanor of Toledo (1522–1562), Duchess of Florence, wife of Cosimo I Fadrique de Toledo (1580–1622), Spanish nobleman and Admiral Francisco Hernández de Toledo (1514–1587), naturalist and court physician to the King of Spain Francisco de Toledo, Count of Oropesa (1515–1584), Spanish Viceroy of Peru Juan Bautista de Toledo (c.1515–1567), Spanish architect María de Toledo (1490–1549), Vicereine of the Spanish Colony of Santo Domingo Pedro Álvarez de Toledo, 2nd Marquis of Villafranca (1484–1553) Viceroy of Naples Pedro de Toledo, 1st Marquis of Mancera (1585–1654), Spanish Viceroy of Peru

Contemporary Adam Toledo (2007–2021), Mexican American boy fatally shot by police Alejandro Toledo (b. 1946), 63rd President of Peru Amelia Toledo (1926–2017), Brazilian artist Antonio Toledo Corro (1919–2018), Mexican politician Ary Toledo (1937–2024), Brazilian humorist, singer, lyricist and actor Baldomero Toledo (b. 1970), American football (soccer) referee Beline Toledo (b. 2002), Mexican footballer Bob Toledo (b. 1946), American college football coach Cícero Pompeu de Toledo (1910–1959), Brazilian president of São Paulo FC Francisco Toledo (1940–2019), contemporary Mexican artist Filipe Toledo (b. 1995), Brazilian professional surfer Gabriel Toledo, (b. 1991), known as FalleN, Brazilian Counter-Strike player Goya Toledo (b. 1969), Spanish actress and model Guillermo Toledo (b. 1970), Spanish actor, producer and political activist Hernán Toledo (b. 1996), Argentinian football (soccer) player Isabel Toledo (1961–2019), Cuban-American fashion designer Javier Toledo (b. 1986), Argentinian football (soccer) player José Victor Toledo (1931–1980), American federal judge Juan Pedro Toledo (b. 1978), Mexican sprint athlete Klebber Toledo (b. 1986), Brazilian actor and model Mario Monteforte Toledo (1911–2003), Guatemalan writer and politician Mirta Toledo (b. 1952), Argentinian artist Natalia Toledo (b. 1968), Mexican poet Natalia Toledo (athlete) (b. 1972), Paraguayan track & field athlete Oliver Toledo (b. 1987), Chilean football (soccer) player Patchy Toledo (b. 1978), Brazilian football (soccer) player Rafael Toledo (b. 1980), Brazilian football (soccer) player Robson Toledo (b. 1981), Brazilian football (soccer) player Víctor Manuel Toledo (b. 1945), Mexican biologist and politician Will Toledo, (b. 1992), American singer/songwriter, frontman of Car Seat Headrest