Hargis is a surname. Notable people with the surname include:
Billy James Hargis (1925–2004), American evangelist Denver David Hargis (1921–1989), American politician Frankie Hargis (1965–2021), Cherokee politician Gary Hargis (born 1956), American baseball player John Hargis (swimmer) (born 1975), American swimmer John Hargis (basketball) (1920–1986), American basketball player V. Burns Hargis, American academic administrator
Places Hargis, Kentucky, unincorporated community, United States Hargis, Louisiana, unincorporated community, United States