Handford is a surname. Notable people with the surname include:
Alick Handford (1869–1935), English cricketer Clive Handford (born 1937), Anglican bishop Frank Handford, English rugby union player James Handford (1890–1948), English cricketer Martin Handford (born 1956), English writer and illustrator Peter Handford (1919–2007), English audio engineer Phil Handford (born 1964), English footballer Richard Handford, British television producer Sanders Handford (1858–1917), English-born American cricketer
In fiction Julius Handford, an alias for John Harmon in Dickens's Our Mutual Friend Mr. Handford, a character in Sesame Street
See also Handforth (surname) Hanford (disambiguation)