Seelye is a surname. Notable people with the surname include:
Elizabeth Eggleston Seelye (1858-1923), American writer Frederick Thomas Seelye (1879–1962), New Zealand chemist and academic Gilbert T. Seelye (1877–1928), New York politician Julius Hawley Seelye (1824–1895), American missionary, writer and politician Kate Seelye, American journalist Laurenus Clark Seelye (1837–1924), American college president Talcott Williams Seelye (1922–2006), American diplomat and writer
See also Seeley (surname) Seelye Brook