Greason is a surname. Notable people with the surname include:
A. LeRoy Greason (1922–2011), the twelfth president of Bowdoin College Bill Greason (born 1924), retired American baseball player, became a Baptist minister Jeff Greason, founder of XCOR Aerospace, the Commercial Spaceflight Federation John Greason (1851–1889), American professional baseball player Murray Greason (1901–1960), American college basketball and baseball coach Staci Greason (born 1964), American actress Thomas Greason (born 1970), Republican member of the Virginia House of Delegates