What Can I Do? may refer to:

"What Can I Do?" (Édith Piaf song), 1950 "What Can I Do" by Smokie from Midnight Café, 1976 "What Can I Do?" (Ice Cube song), 1994 "What Can I Do?" (The Corrs song), 1998 "What Can I Do" (The Black Belles song), 2010 "What Can I Do" by Gotthard from Human Zoo, 2003