Thwaite is an English surname. Notable people with this surname include the following:
Ann Thwaite (born 1932), British biographer Anthony Thwaite (1930–2021), English poet and writer Bruce Thwaite (1923–1991), Australian paralympic competitor Mark Thwaite (born 1965), English guitarist Michael Thwaite (born 1983), Australian soccer player
See also Thwaites (surname)