Lonesome Lake could refer to:
United States Lonesome Lake (Idaho), an alpine lake in Custer County, Idaho Lonesome Lake (Montana), a lake located in Carbon County, Montana Lonesome Lake (New Hampshire), a lake located in Franconia Notch in the White Mountains of New Hampshire Lonesome Lake (Washington), a lake in the Mount Baker–Snoqualmie National Forest Lonesome Lake (Wyoming), a lake in the Wind River Range
Canada Lonesome Lake (British Columbia), a lake located in Tweedsmuir South Provincial Park, British Columbia near Hunlen Falls Lonesome Lake (Nipissing District), Ontario Lonesome Lake (Algoma District), Ontario