Manucci is an Italian surname. Notable people with the surname include:
Amatino Manucci, inventor of double-entry bookkeeping Teobaldo Manucci (1449/1452 – 1515), Italian humanist, scholar, educator, and the founder of the Aldine Press Niccolao Manucci (1639–1717), Italian writer and traveller Paolo Manucci, or Mannucci (born 1942), Italian former racing cyclist Dan Manucci (born 1957), American football quarterback
See also Mannucci