Iodized salt (also spelled iodised salt) is table salt mixed with a minuscule amount of various iodine salts. The ingestion of iodine prevents iodine deficiency. Worldwide, iodine deficiency affects about two billion people and is the leading preventable cause of intellectual and developmental disabilities. Deficiency also causes thyroid gland problems, including endemic goitre. In many countries, iodine deficiency is a major public health problem that can be cheaply addressed by purposely adding small amounts of iodine to the sodium chloride salt.

Iodine is a micronutrient and dietary mineral that is naturally present in the food supply in some regions (especially near sea coasts) but is generally quite rare in the Earth's crust. Where natural levels of iodine in the soil are low and vegetables do not take up the iodine, iodine added to salt provides the small but essential amount of iodine needed by humans.

An opened package of table salt with iodide may rapidly lose its iodine content in high temperature and high relative humidity conditions through the process of oxidation and iodine sublimation.Diosady, L. L., and M. G. Venkatesh Mannar. "Stability of iodine in iodized salt". 8th World Salt Symposium. Amsterdam: Elsevier. 2000. Poor manufacturing techniques and storage processes can also lead to insufficient amounts of iodine in table salt.

Chemistry, biochemistry, and nutritional aspects

Four inorganic compounds are used as iodine sources, depending on the producer: potassium iodate, potassium iodide, sodium iodate, and sodium iodide. Any of these compounds supplies the body with the iodine required for the biosynthesis of thyroxine (T4) and triiodothyronine (T3) hormones by the thyroid gland. Animals also benefit from iodine supplements, and the hydrogen iodide derivative of ethylenediamine is the main supplement to livestock feed.Phyllis A. Lyday "Iodine and Iodine Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. .

Salt is an effective vehicle for distributing iodine to the public because it does not spoil and is consumed in more predictable amounts than most other commodities. For example, the concentration of iodine in salt has gradually increased in Switzerland: 3.75 mg/kg in 1922, 7.5 mg/kg in 1962, 15 mg/kg in 1980, 20 mg/kg in 1998, and 25 mg/kg since 2014. These increases were found to improve iodine status in the general Swiss population.

Salt that is iodized with iodide may slowly lose its iodine content by exposure to excess air over long periods.Katarzyna Waszkowiak & Krystyna Szymandera-Buszka. Effect of storage conditions on potassium iodide stability in iodized table salt and collagen preparations. International Journal of Food Science & Technology. Volume 43 Issue 5, Pages 895–899. (Published Online: 27 Nov 2007). Salts fortified with iodate are relatively stable to storage and heat; the main concern is reducing impurities in the salt itself, which can be removed relatively easily. Moisture accelerates the decomposition of iodate, but ceases to do so once reducing impurities are removed.

Contrary to popular assumptions, iodized salt cannot be used as a substitute for potassium iodide (KI) to protect a person's thyroid gland in the event of a nuclear emergency. There is not enough iodine in iodized salt to block the uptake of radioactive iodine by the thyroid.

Production

Edible salt can be iodized by spraying it with a potassium iodate or potassium iodide solution. 57 grams of potassium iodate, costing about US$1.15 (in 2006), is required to iodize a short ton (2,000 pounds) of salt. Optional additives include: Stabilizers such as dextrose (typically at about 0.04%) and sodium thiosulfate, which prevent potassium iodide from oxidizing and evaporating. These ingredients are not required for potassium iodate, which is commonly used globally for its increased stability, but is not approved by the US FDA. Anti-caking agents such as calcium silicate and sodium ferrocyanide, which prevent clumping.

Public health initiatives

Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual and developmental disabilities. According to public health experts, iodization of salt may be the world's simplest and most cost-effective measure available to improve health, only costing US$0.05 per person per year. At the World Summit for Children in 1990, a goal was set to eliminate iodine deficiency by 2000. At that time, 25% of households consumed iodized salt, a proportion that increased to 66% by 2006.

Salt producers are often, although not always, supportive of government initiatives to iodize edible salt supplies. Opposition to iodization comes from small salt producers who are concerned about the added expense, private makers of iodine pills, concerns about promoting salt intake, and unfounded rumours that iodization causes AIDS or other illnesses.

The United States Food and Drug Administration recommends 150 micrograms (0.15 mg) of iodine per day for adults. While iodine is crucial, the FDA also recommends limiting overall sodium intake to less than 2,300 mg per day for adults, which is approximately 1 teaspoon of table salt.

Argentina Since 8 May 1967 salt for human or animal use must be iodized, according to the Law 17,259. Australia Australian children were identified as being iodine deficient in a survey conducted between 2003 and 2004. As a result of this study the Australian Government mandated that all bread except "organic" bread must use iodized salt. There remains concern that this initiative is not sufficient for pregnant and lactating women.

Brazil Iodine Deficiency Disorders were detected as a major public health issue by Brazilian authorities in the 1950s when about 20% of the population had a goitre. The National Agency for Sanitary Vigilance (ANVISA) is responsible for setting the mandatory iodine content of table salt. The Brazilian diet averages 12 g of table salt daily, more than twice the recommended value of 5 g daily. To avoid excess consumption of iodine, the iodizing of Brazilian table salt was reduced to 15–45 mg/kg in July 2013. Specialists criticized the move, saying that it would be better for the government to promote reduced salt intake, which would solve the iodine problem as well as reduce the incidence of high blood pressure.

Canada For table and household use, salt sold to consumers in Canada must be iodized with 0.01% potassium iodide. Sea salt and salt sold for other purposes, such as pickling, may be sold uniodized.

China Much of the Chinese population lives inland, far from sources of dietary iodine. In 1996, the Chinese Ministry of Public Health estimated that iodine deficiency was responsible for 10 million cases of intellectual developmental disorders in China. Chinese governments have held a legal monopoly on salt production since 119 BCE and began iodizing salt in the 1960s, but the reform and opening up in the 1980s led to widespread smuggling of non-iodized salt from private producers. In the inland province of Ningxia, only 20% of the salt consumed was sold by the China National Salt Industry Corporation. The Chinese government responded by cracking down on smuggled salt, establishing a salt police with 25,000 officers to enforce the salt monopoly. Consumption of iodized salt reached 90% of the Chinese population by 2000.

India India and all of its states ban the sale of non-iodized salt for human consumption. However, implementation and enforcement of this policy are imperfect; a 2009 survey found that 9% of households used non-iodized salt and that another 20% used insufficiently iodized salt.

Iodized salt was introduced to India in the late 1950s. Public awareness was increased by special programs and initiatives, both governmental and non-governmental. Currently, iodine deficiency is only present in a few isolated regions which are still unreachable. In India, some people use Himalayan rock salt. Rock salt however is low in iodine and should be consumed only when other iodine-rich foods are in the diet.

Iran A national program with iodized salt started in 1992. A national survey of 1990 revealed the prevalence of iodine deficiency to be 20–80% in different parts of Iran indicating a major public health problem. Central provinces, far from the sea, had the highest prevalence of iodine deficiency. The national salt enrichment program was very successful. The prevalence of goiter in Iran dropped dramatically. The national survey in 1996 reported that 40% of boys and 50% of girls have goiter. The 3rd national survey in 2001 showed that the total goiter rate is 9.8%. In 2007, the 4th national survey was conducted 17 years after iodized salt consumption by Iranian households. In this study, the total goiter rate was 5.7%.

Concerns of iodine deficiency have raised over recent years due to the consumption of non-iodized salts especially sea salt which is strongly suggested by traditional medicine workers in Iran, many of whom lack a pertinent academic background.

Kazakhstan Kazakhstan, a country in Central Eurasia in which local food supplies seldom contain sufficient iodine, has drastically reduced iodine deficiency through salt iodization programs. Campaigns by the government and non-profit organisations to educate the public about the benefits of iodized salt began in the mid-1990s, with iodization of edible salt becoming legally mandatory in 2002.

Malaysia Salt being sold in the country must be iodized which is forced under the Food Regulation 1985 from 30 September 2020.

Nepal The Salt Trading Corporation has been distributing iodized Salt in Nepal since 1963. 98% of the Population uses iodized Salt. Utilising non-iodized salt for human consumption is prohibited. Salt costs about US$0.27 a kilo.

Philippines On December 20, 1995, Philippine President Fidel V. Ramos signed Republic Act 8172: An Act for Salt Nationwide (ASIN). However, local production of non-iodized salt continues. Romania According to the 568/2002 law signed by the Romanian parliament and republished in 2009, since 2002 iodized salt has been distributed mandatory in the whole country. It is used mandatory on the market for household consumption, in bakeries, and for pregnant women. iodized salt is optional though for animal consumption and the food industry, although widely used. The salt iodization process has to ensure a minimum of 30mg iodine/kg of salt.Sustainable Prevention of Iodine Deficiency and Achievement of Optimal Iodine Nutrition – Romania http://www.ign.org/cm_data/Poster_Romania.pdf DECISION no. 568 of 5 June 2002 (republished) https://legislatie.just.ro/Public/DetaliiDocument/36611

South Africa The South African government instructed that all salt for sale would be iodized after December 12, 1995.Health Hints, Cerebos Impact after 1 year of compulsory iodization on the iodine content of table salt at retailer level in South Africa , 1999, vol. 50, no. 1, pp. 7–12 (12 ref.), International journal of food sciences and nutrition ISSN 0963-7486

Switzerland Switzerland was the first country to introduce iodized salt, in the world's first food fortification program.

In the early 20th century, goitre was endemic in most Swiss cantons. Iodine was recognized to have an effect on goitre, but it was not until Heinrich Hunziker, a GP in Adliswil, argued that the necessary dose of iodine was minute (with larger amounts causing overdose issues), and another doctor, Otto Bayard, conducted successful experiments based on this idea, that the theory of goitre as iodine deficiency came to be accepted. Learning of Hunziker's theory, Bayard conducted experiments with iodized salt containing only tiny amounts of iodine in villages badly affected by goitre. The success of these led, starting in 1922, to the adoption of iodized salt throughout the Swiss cantons.