Grimsley is a surname. Notable people with the surname include:
Chet Grimsley (born 1956), American football player Crawford Grimsley (born 1967), American boxer and kickboxer Denise Grimsley (born 1959), American politician Greer Grimsley, American opera singer Jack Grimsley, Australian musician James Grimsley, Jr. (1921–2013), United States Army general Jason Grimsley (born 1967), American baseball player Jim Grimsley (born 1955), American writer John Grimsley (1962–2008), American football player Ross Grimsley (born 1950), American baseball player Ross Grimsley (1950s pitcher) (1922–1994), American baseball player