Aguinaga is a surname of Basque origins. Notable people with the surname include:
Alejandro Aguinaga (born 1950), Peruvian physician and politician Álex Aguinaga (born 1968), Ecuadorian footballer and manager Daniel Aguiñaga (born 1994), Mexican footballer Javi Martínez (Javier Martínez Aguinaga, born 1988), Spanish footballer Juan Aguinaga (born 1978), Ecuadorian footballer Marcela Aguiñaga (born 1973), Ecuadorian politician