Agostinelli is an Italian-language patronymic surname. Notable people with the surname include:
Alessandro Agostinelli (born 1965), Italian writer and journalist Andrea Agostinelli (born 1957), Italian footballer and coach Bruno Agostinelli (1987–2016), Canadian tennis player Cataldo Agostinelli (1894–1988), Italian mathematician Donatella Agostinelli (born 1974), Italian politician Franco Agostinelli (born 1944), Italian prelate Massimo Agostinelli (born 1987), Swiss-based Italian American artist
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