Mission House may refer to:
United States
First Mission House, Bethel, Alaska Old Mission House, Fort Yukon, Alaska Mission House (Stockbridge, Massachusetts) Mission House (Mackinac Island), Michigan
Other countries Bodden Town Mission House, Grand Cayman Hermannsburg Mission House, Hermannsburg, KwaZulu-Natal, South Africa Kemp House, also known as Mission House, Kerikeri, New Zealand Moravian Brethren Mission House, Nuuk, Greenland
See also Mission Houses Museum, Honolulu, Hawaii Church Missions House, New York City Mission station