Melrose is both a surname and a given name. Notable people with the surname include:
Surname Alex Melrose (1865–1944), South Australian lawyer and art patron Alexander Melrose (1889–1962), South Australian politician Barry Melrose (1956–2026), head coach of the National Hockey League's Tampa Bay Lightning & Los Angeles Kings Charles James Melrose (1913–1936), Australian aviator and holder of early flight records between Australia and other countries David Melrose, Scottish wheelchair curler Dianna Melrose (born 1952), British diplomat, ambassador to Cuba Fiona Melrose (born 1973), South African novelist George Melrose (1806–1894), pioneer in South Australia Graham Melrose (born 1949), Australian rules footballer Jim Melrose (born 1958), Scottish footballer Joseph Melrose (1944–2014), American diplomat who served as United States Ambassador to Sierra Leone Richard Burt Melrose (born 1949), Australian mathematician Robert Thomson Melrose (1862–1945), pastoralist and politician in South Australia
Given name
Melrose Bickerstaff, who appeared in America's Next Top Model season 7, which ran in 2006