Amsel is a surname. Notable people with the surname include:

Beth Amsel, singer-songwriter Hans Georg Amsel (1905–1999), German entomologist Richard Amsel (1947–1985), American illustrator and graphic designer Lena Amsel (1898–1928), was a dancer and actress. Fictional characters: General Heinrich Amsel, Nazi general and antagonist in Call of Duty: World at War

See also Juraj Amšel, water polo player