McCafferty is a surname of Irish origin. It is derived from the Irish Mac Eachmharcaigh, meaning "son of Eachmharcach". Notable people with the surname include:
Archie McCafferty, Scottish-born Australian serial killer Bill McCafferty (1882–1929), Scottish footballer Christine McCafferty (born 1945), English politician Dan McCafferty (1946–2022), Scottish singer Don McCafferty (1921–1974), American footballer and coach Ian McCafferty (born 1944), Scottish athlete Ian McCafferty (born 1956), British economist Jack McCafferty (1914–1999), Australian businessman Jane McCafferty, American writer John McCafferty, British scientist John Edgar McCafferty (1920–1980), American Catholic bishop Megan McCafferty (born 1973), American writer Neil McCafferty (born 1984), Northern Irish footballer Nell McCafferty (1944–2024), Irish journalist and playwright Owen McCafferty (born 1961), Northern Irish playwright