Salzer, otherwise Saltzer and Sälzer, is a German surname meaning "salter". Notable people with this surname include the following:
Bernhard Sälzer (1940–1993), German MEP Bruno Sälzer (born 1957), German CEO of Escada, international luxury fashion group Else Rambausek-Salzer (1907–1994), Austrian actress and singer Felix Salzer (1904–1986), Austrian-American music theorist and musicologist František Salzer (1902–1974), Czech actor and director Friedrich Salzer (1827–1876), German landscape painter Jerry Saltzer (born 1939), American computer scientist Lisel Salzer (1906–2005), Austrian-born American painter Monika Salzer (born 1948) Austrian psychotherapist, Protestant theologian and pastor, columnist, and author Otto Salzer (1874–1944), German racing car driver Robert Samuel Salzer (1919–1988), Vice Admiral of the United States Navy