Adenosylcobinamide-phosphate synthase

Adenosylcobinamide-phosphate synthase (, CbiB) is an enzyme with systematic name adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming). This enzyme catalyses the following chemical reaction

(1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate ADP + phosphate + adenosylcobinamide phosphate (2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol ADP + phosphate + adenosylcobinamide

One of the substrates, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (). This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.

See also Cobalamin biosynthesis

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