3-Hydroxybenzoate—CoA ligase (, 3-hydroxybenzoyl-CoA synthetase, 3-hydroxybenzoate-coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase) is an enzyme with systematic name 3-hydroxybenzoate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction
ATP + 3-hydroxybenzoate + CoA AMP + diphosphate + 3-hydroxybenzoyl-CoA
The enzyme works equally well with 4-hydroxybenzoate.
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