Rook is a surname. Notable people with the surname include:

Ada Rook, Canadian musician Alan Rook (1909-1990), editor of the 1936 issue of New Oxford Poetry, one of the Cairo poets Chad Rook (born 1982 or 1983), Canadian actor Jean Rook (1931–1991), British newspaper columnist John Rook (1937-2016), American radio programmer Jerry Rook (1943-2019), American former professional basketball player Susan Rook (born 1961), journalist and photographer

See also Rooks (surname)