Gentileschi () is an Italian surname, notably borne by a family of Italian artists. These include:
Artemisia Gentileschi (1593 – ), Italian painter, daughter of Orazio Francesco Gentileschi (1597 – ), Italian painter, son of Orazio and brother of Artemisia Orazio Gentileschi (1563–1639), Italian painter, father of Artemisia and Francesco
See also 14831 Gentileschi, a minor planet named after Artemisia Gentileschi