Lethbridge is a surname. Notable people with the surname include:
Alice Lethbridge (1866–1948), English music hall dancer and Gaiety Girl Arthur Lethbridge (Ivor of Ivor Moreton and Dave Kaye) (1908–1984), British singer and pianist
Christopher Lethbridge (cricketer) (born 1961), English cricketer Grace Marguerite Lethbridge or Grace Marguerite Hay Drummond-Hay (1895–1946), the first woman to travel around the world by air John Lethbridge (1675–1759), inventor of an early diving apparatus in 1715 John Sydney Lethbridge (1897–1961), British soldier Julian Lethbridge (born 1947), British painter Robert Lethbridge (born 1947), professor of French and Master of Fitzwilliam College Cambridge Robert Lethbridge (politician), Australian politician Roper Lethbridge (1840–1919), British academic and civil servant in India T. C. Lethbridge (1901–1971), British explorer, author, archaeologist and psychic researcher Timothy C. Lethbridge (born 1963), Canadian computer scientist and Professor, University of Ottawa William Lethbridge (1825–1901), after whom the city of Lethbridge, Alberta, was named Nemone Lethbridge (1932–present), barrister and playwright. Daughter of John Sydney Lethbridge
Fictional characters: Brigadier Lethbridge-Stewart, a character on the television show Doctor Who