Groff is an anglicized form of the surname Graf or Graff and of predominantly Swiss and sometimes German origin. Notable people with the surname include:
Jonathan Groff (born 1985), American actor and singer Jonathan Groff, American comedy writer Lauren Groff (born 1978), American writer Mike Groff (born 1961), American racing driver Peter Groff (born 1963), American politician from Colorado Richard F. "Regis" Groff (1935-2014), American politician from Colorado Robbie Groff (born 1966), American racing driver Ulysses Grant Groff (1865–1950), American landowner and philanthropist Skip Groff (1948–2019), American record producer Sarah True (née Groff, born 1981), American triathlete