Grondona is an Italian surname. Notable people with the surname include:

Benjamín Grondona Argentine rugby union player Gustavo Grondona, Argentine footballer Humberto Grondona, Argentine football coach Jaime Grondona, Chilean footballer Julio Grondona, Argentine football executive Mariano Grondona, Argentine journalist Stefano Grondona, Italian guitarist Santiago Grondona Argentine rugby union player

See also Grondona, Piedmont, a comune (municipality) in the Province of Alessandria, Italy