4′-Demethylrebeccamycin synthase (EC 4.3.3.5, arcyriaflavin A N-glycosyltransferase, RebG) is an enzyme with systematic name 4′-demethylrebeccamycin D-glucose-lyase. It catalyses the following chemical reaction

This is a late step in the biosynthesis of rebeccamycin.

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