La Harpe is a surname. Notable people with the surname include:
Amédée Emmanuel François Laharpe (1754–1796), French general and cousin of Frédéric-César Darryl de la Harpe (born 1986), Namibian rugby union player Deborah-Anne De la Harpe (born 2000), Australian footballer Frédéric-César de La Harpe (1754–1838), Swiss politician and tutor to the Tsar of Russia Jean-Baptiste Bénard de la Harpe (1683–1765), French explorer Jean-François de La Harpe (1739–1803), French playwright, writer and critic Philippe de La Harpe (1830–1882), Swiss paleontologist Ryan de la Harpe (born 1982), Namibian rugby union player