(−)-α-Pinene synthase (EC 4.2.3.119, (−)-α-pinene/(−)-camphene synthase, (−)-α-pinene cyclase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing, (−)-α-pinene-forming]. This enzyme catalyses the following chemical reaction
geranyl diphosphate (−)-α-pinene + diphosphate
Cyclase II of Salvia officinalis (sage) gives about equal parts (−)-α-pinene, (−)-β-pinene and (−)-camphene.
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