α-Gurjunene synthase (EC 4.2.3.72) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((–)-α-gurjunene-forming). This enzyme catalyses the following chemical reaction
(2E,6E)-farnesyl diphosphate (–)-α-gurjunene + diphosphate
Initial cyclization probably gives bicyclogermacrene in an enzyme-bound form.
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