Ent-copalyl-diphosphate diphosphate-lyase may refer to: Ent-cassa-12,15-diene synthase, an enzyme Ent-sandaracopimaradiene synthase, an enzyme Ent-pimara-8(14),15-diene synthase, an enzyme Ent-pimara-9(11),15-diene synthase, an enzyme Ent-isokaurene synthase, an enzyme