UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (, PglF) is an enzyme with systematic name UDP-N-acetyl-α-Dglucosamine hydro-lyase (configuration-retaining; UDP-2-acetamido-2,6-dideoxy-α-Dxylo-hex-4-ulose-forming). This enzyme catalyses the following chemical reaction
UDP-N-acetyl-α-D-glucosamine UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose + H2O
This enzyme contains NAD+ as a cofactor.
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