N-acetylmuramic acid 6-phosphate etherase (, MurNAc-6-P etherase, MurQ) is an enzyme with systematic name (R)-lactate hydro-lyase (adding N-acetyl-D-glucosamine 6-phosphate; N-acetylmuramate 6-phosphate-forming). It catalyses the following chemical reaction
The reaction cleaves a lactic acid group from the substrate, giving N-acetyl-D-glucosamine 6-phosphate.
This enzyme characterised from Escherichia coli acts, in some Pseudomonadota, with anhydro-N-acetylmuramic acid kinase to allow recycling of cell wall components via 1,6-anhydro-N-acetyl-β-muramic acid.
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