Peptidyl-glutamate 4-carboxylase

Peptidyl-glutamate 4-carboxylase (, vitamin K-dependent carboxylase, gamma-glutamyl carboxylase) is an enzyme with systematic name peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing). This enzyme catalyses the following chemical reaction

peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O peptidyl-glutamate + CO2 + O2 + phylloquinone

The enzyme can use various vitamin-K derivatives, including menaquinone.

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