Speller is a surname. Notable people with the surname include:
Frank Speller, American organist and academic Fred Speller (1863–1909), English footballer Émile Speller (1875–1952), Luxembourgish military officer Frank Newman Speller (1875–1968), Canadian-born American metallurgical engineer Henry Speller (1900–1997), American artist and blues musician Tony Speller (1929–2013), British politician Georgia Speller (1931–1987), African American artist Bob Speller (1956–2021), Canadian politician Sylvia Speller (born 1967), German physicist Cara Speller (born 1972), British film maker and producer Edward Speller (born 2002), British YouTuber Cody Speller (born 1994), Canadian professional football player