Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase (, Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase, ADPRibase-Mn) is an enzyme with systematic name CDP-choline phosphohydrolase. This enzyme catalyses the following chemical reaction

(1) CDP-choline + H2O CMP + phosphocholine (2) ADP-ribose + H2O AMP + D-ribose 5-phosphate

This enzyme requires Mn2+, which cannot be replaced by Mg2+.

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