Fibrolase (, fibrinolytic proteinase, Agkistrodon contortrix contortrix metalloproteinase, Agkistrodon contortrix contortrix venom metalloproteinase) is an enzyme. This enzyme catalyses the following chemical reaction
Hydrolysis of -Ala14-Leu- in insulin B chain and -Lys413-Leu- in alpha-chain of fibrinogen
This enzyme is present in the venom of the southern copperhead snake (Agkistrodon contortrix contortrix).
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